NANO CURCUMIM (NANO COMPONENT OF CURCUMA LONGA/HARIDRA)
Curcuma longa that is Turmeric is a popular Inidian spice has been used for thousands of years. Not only for cooking but also as medicinal herb. In India Turmeric is used to treat several medical conditions, In fact it’s a staple of Ayurvedic medicine. Turmeric belonging to the zingibeaceae/ginger family. This plant is extensively cultivated in south India.
Chemically curcumin is a diarylheptanoid, belonging to the group of curcuminoids which are natural phenols responsible for turmeric’s yellow colour.
There are three curcuminoids present in Turmeric
1] curcumin
2] desmethoxy curcumin
3] bisdesmthoxy curcumin
Root (underground stem) of this plant is processed to from turmeric which contains 2% to 5% curcumin. It may required consuming more curcumin than a person eats in typical diet to experience the full effects.
Last many years curcumin has been the subject of great interest for medical world due to its special medicinal properties.
Curcumin aids in the management of oxidative and inflammatory conditions, hyperlipidenia, anxiety, metabolic syndrome and especially in arthritis.
It has antioxidant, anti-inflammatory, antimutagenic, antimicrobial, and anticancer properties.
Antioxidant & anti-inflammatory properties are two primary mechanism that explain effects of curcumin on various disease.
ANTIOXIDANT ACTION
Curcumin can scavange different types of free radicals such as ROS (reactive oxygen spices) & RNS (reactive nitrogen spices)
Curcumin regulates the activity of GHH, catalase and SOD enzymes active in the neutralization of free radicals.
Curcumin also in it ROS generating enzymes such as xanthine hydrogenase, lipoxygenase.
Curcumin known as breaking anti-oxidant like vit E, It can effectively scavenge peroxyl redicals.
ANTI-INFLAMMATORY ACTION
Oxidative stress has been involved in many chronic diseases, its organic process is related to inflammation.
Inflammatory cells liberate a number of reactive spices at the site of inflammation leading to oxidative stress, which shows close relation of oxidative stress & inflammation. In addition, number of ROS, RNS can initiate intracellular signaling cascade that increase pro-inflammatory gene expression.
Tumor necrosis factor alpha(TNF alpha) is a major mediator of inflammation in many diseases.
This effect is regulated by activation of transcription factor, nuclear factor (NF-B). Where TNF alpha is known to be most potent NF-KB activator, NF-KB regulates expression of TNF alpha.
NF-KB is also activated by inflammatory cytokines, gram negative bacteria, viruses, pollutants, chemical/physical/mechanical/psychological stress, high glucose, ultraviolet rays, cigarette smoke and many disease causing factors.
Therefore, the agents that down-regulates NF-KB & its gene product are efficient against several disease.
Curcumin has been shown blocking NF-KB activation. Curcumin has also shown suppressing inflammation. Hence curcumin is a potential component with anti-inflammatory activity.
Curcumin has been studied long time for its use in arthritis.
Arthritis shows two major types of it, osteoarthritis and rheumatoid arthritis. Curcumin has shown beneficial results in both.
Osteoarthritis Arthritis is a degenerative disease of joint and has in inflammatory cause. Curcumin is natural herb component having anti-inflammatory and antioxidant properties, hence beneficial for improving joints inflammation and degeneration.
Rheumatoid Arthritis is an auto immune condition, which means that the body’s immune system mistakenly attacks healthy joint tissue. These attacks cause inflammation that leads bone & joint damage eventually. The natural anti-inflammatory and antioxidant properties of curcumin can benefit people with RA.
CURCUMIN’S ANTI CANCER EFFECT
A number of cancer have been studied that may be treated with curcumin. Such as blood cancer, lung cancer, skin cancer, intestinal cancer, pancreatic cancer, cancer of the mouth and oral cavity.
MECHANISM
1] Suppression of cellular transformation.
When healthy cells transform into cancer cells, cancer disease rise up and those cancer then multiply and spread.
Curcumin has shown efficacy to reduce this process.
2] Prevention of cancer cell growth.
Cancer cells multiply rapidly and also avoid apoptosis (a mechanism of programmed cell death that is intended to kill them).
Curcumin prevents this growth by breaking the cell cycle & causing programmed cell death.
3] Suppression of carcinogenic effects.
The body is exposed to many toxins, carcinogens that increase the risk of cellular transformation and cancer.
Curcumin also activates carcinogen detoxifying enzymes which protects body from causing cancer.
4] Suppression of metastasis.
Curcumin shows anticancer property by regulation of inflammatory cytokimes, growth factors, transcription factors, protein kinases & some enzymes.
- Natural Immunity Booster.
- Natural Rejuvenatory and Tonic product.
- Helps to maintain overall body health with protecting all vital organs.
- Unique element “Curcumin” use.
- Antioxidant, Anti inflammatory, Anti Microbial, Antiviral, Anti Cancer
- Distinct description of curcumin available in ancient Ayurveda literature.
- Formulated by Ayurveda experts.
Tab Content
Degenerative musculo – skeletal disorders.
Arthritis & Rheumatism.
Cold, cough, sinusitis.
Diabetes.
High blood pressure, cholesterol, heart diseases.
Stress, depression, anxiety, alzheimer’s disease.
Skin and hair problems.
Fatigue / emaciation.
Vitamin and mineral deficiency diseases.
- One capsule daily after meal or as prescribed by the physician.
Each Capsule Contains:
Nano Curcumin 500mg
Bioprine 10mg

